Cochlear Implant Recipients
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Basic conditions: Subjects must be aged 18 to 65, be right-handed, and have Chinese as their native language. In addition, subjects must voluntarily participate in this study and sign the informed consent form; 2. Hearing and surgical requirements: Subjects must meet the preoperative assessment criteria in the "Cochlear Implantation Practice Guidelines." They should be diagnosed with bilateral severe to profound sensorineural hearing loss (pure tone threshold >= 80 dB HL) and show no significant improvement after hearing aid intervention. Imaging examinations must exclude inner ear malformations, and after multidisciplinary evaluation, they must be deemed suitable to undergo cochlear implantation surgery; 3. Health and function: Subjects must have no language, motor, or cognitive impairments, and no history of brain injury or neurological disease. In addition, subjects must not be using any medications that could affect nervous system function. Subjects must have normal vision and be able to cooperate to complete experimental tasks.
Exclusion criteria
Exclusion criteria: 1. Subjects with any language, motor, or cognitive disorders (such as aphasia, motor speech disorders, or articulation disorders) that may affect the assessment of brain function; 2. Subjects with a history of brain injury or neurological diseases (such as stroke, epilepsy, etc.); 3. Subjects currently using medications that affect nervous system function (such as sedatives, antipsychotics, or other central nervous system drugs) that may impact brain activity or the reliability of experimental data; 4. Subjects with inner ear malformations or other severe ear diseases that may affect the outcome of cochlear implant surgery; 5. Subjects who do not meet the medical indications for cochlear implantation or have not undergone relevant multidisciplinary assessment; 6. Subjects with severe ophthalmic problems or visual impairments that prevent them from completing experimental tasks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| speech recognition accuracy ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cortical Activation;Cortical Functional Connectivity; | — |
Countries
China
Contacts
Shuguang Hospital affiliated to Shanghai University of TCM