Skip to content

Underwater cold snare polypectomy (UCSP) for the treatment of 10-19mm non-pedunculated colorectal polyps: a single-blind, single-center, randomized controlled clinical study

Underwater cold snare polypectomy (UCSP) for the treatment of 10-19mm non-pedunculated colorectal polyps: a single-blind, single-center, randomized controlled clinical study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600120611
Enrollment
Unknown
Registered
2026-03-17
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal polyps

Interventions

Conventional Cold Snare Polypectomy (CCSP):Conventional Cold Snare Polypectomy (CCSP): Standard colonoscopy with insufflation, without water immersion of the polyp, using a snare to resect and excise
Underwater Cold Snare Polypectomy (UCSP):Underwater Cold Snare Polypectomy (UCSP): Aspiration of appropriate amount of air from the intestinal lumen, followed by injection of an adequate amount of roo

Sponsors

Tangdu Hospital, Fourth Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 18 and 80 years; 2. Non-pedunculated colorectal polyps (Paris classification types 0-Is and 0-II) measuring 10–19 mm in diameter, located in the rectum or colon, and eligible for snare polypectomy; 3. Informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with astrointestinal tract malignancy; 2. Patients with inflammatory bowel disease (IBD); 3. Clinically significant coagulation disorders; 4. Patients receiving antithrombotic therapy who have discontinued treatment for less than one week; 5. Hemodialysis patients with a clinically significant bleeding tendency; 6. Severe dysfunction of the heart, lungs, liver, or kidneys, or severe psychiatric disorders; 7. Colon polyps suspected of malignancy with submucosal infiltration, as diagnosed by endoscopy.

Design outcomes

Primary

MeasureTime frame
R0 Resection;

Secondary

MeasureTime frame
Resection Time;Specimen Retrieval Time;Total Procedure Time;Intraoperative Bleeding and Hemostatic Clip Usage Rate;Postoperative Bleeding;Perforation;Depth of Mucosal and Submucosal Resection;Recurrence;Patient Pain Score;

Countries

China

Contacts

Public ContactDou Weijia

Tangdu Hospital, Fourth Military Medical University

weijia_dou@126.com+86 187 9273 9164

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 3, 2026