Dry eye
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 8~16 years old (including 8 years old and 16 years old), male or female; 2. Those who have confirmed myopia with clinical diagnosis, completed routine orthokeratology endoscopy, and wore and followed up regularly; 3. The guardian voluntarily signed the "Informed Consent Form of the Subject".
Exclusion criteria
Exclusion criteria: 1. History of severe allergies, glaucoma, blue eyelids syndrome, ocular hypertension, fundus macular lesions or lesions, etc., do not meet the requirements for wearing orthokeratology lenses; 2. Corneal curvature examination, the average K value of the anterior surface of the cornea >=45; 3. Patients with heart, liver, kidney and other systemic diseases and congenital hereditary myopia; 4. Patients with ocular trauma and chronic eye diseases such as oblique or surgical eye and atopic keratoconjunctivitis; 5. Patients with other eye diseases such as varus trichiasis, severe horn and conjunctival infections; 6. Patients with neurological diseases and allergies or contraindications to atropine drugs or other therapeutic drugs; 7. Patients with albinism, psoriasis, nephrotic syndrome, systemic lupus erythematosus, diabetes and other immune system and systemic diseases; 8. Epilepsy, mental disorders and unable to communicate normally; 9. Those who have received other treatments to control the development of myopia in the past, such as the use of anticholinergic drugs such as atropine within 3 months, or participated in other functional frames, multifocal flexible scopes and other related investigators; 10. Other conditions judged by the investigator to be unsuitable for participating in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blinking Undeturbed Tear Break-Up Time, BUT;Tears River Height;Degree of meibomian gland deficiency; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dry Eye Questionnaire Score; | — |
Countries
China
Contacts
Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine