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Effects of general anesthesia combined with oxybuprocaine hydrochloride eye drops on oculocardiac reflex, agitation and pain during recovery period during strabismus surgery in children

Effects of general anesthesia combined with oxybuprocaine hydrochloride eye drops on oculocardiac reflex, agitation and pain during recovery period during strabismus surgery in children

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600120598
Enrollment
Unknown
Registered
2026-03-17
Start date
2026-03-23
Completion date
Unknown
Last updated
2026-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pediatric strabismus

Interventions

Experimental group:In the experimental group, 1 drop of 0.4% Oxybuprocaine Hydrochloride Eye Drops was instilled into the operated eye before surgery, 1 drop of 0.4% Oxybuprocaine Hydrochloride Eye Dr
Control group:No Oxybucaine Eye Drops.At the end of the operation, tobramycin eye ointment was directly applied to the operated eye

Sponsors

People's Hospital of Ningxia Hui Autonomous Region
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1.Age 3-12 years old, ASA class I-II, elective strabismus surgery under general anesthesia; 2.no cardiovascular and cerebrovascular diseases, respiratory tract infection; 3.signed informed consent form.

Exclusion criteria

Exclusion criteria: Allergic to local anesthetics, family members and children refused to cooperate with follow-up.

Design outcomes

Primary

MeasureTime frame
Incidence of intraoperative oculomotor reflex;Postoperative Pain Behavior Scale (FLACC) score;PACU restlessness score;

Secondary

MeasureTime frame
Postoperative adverse reactions;Operation time, recovery time, extubation time, PACU stay time;

Countries

China

Contacts

Public ContactXue Zhang

People's Hospital of Ningxia Hui Autonomous Region

1433600336@qq.com+86 157 5430 7384

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 3, 2026