Acute cerebral infarction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Diagnosis of acute cerebral infarction meeting the stroke diagnostic criteria outlined in the 2018 Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke established by the Cerebrovascular Disease Group of the Neurology Branch of the Chinese Medical Association; 2.Time from last normal appearance to hospital admission between 4.5 and 24 hours; 3.NIHSS score >= 4; 4.Age between 18 and 80 years; 5.Pre-onset modified Rankin Scale (mRS) score of 0–1;
Exclusion criteria
Exclusion criteria: 1.Patients unable to undergo cranial multimodal MRI examination or with poor image quality rendering analysis impossible; 2.Patients with unstable vital signs; 3.Patients confirmed via CT or MRI at admission to have cerebral infarction complicated by hemorrhage or tumor; 4.Severe stroke (NIHSS score > 25); 5.Patients with severe cardiac, hepatic, renal, or pulmonary dysfunction, or coagulation disorders; 6.Patients undergoing endovascular intervention.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Baseline data, NIHSS scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Rates of incidence rates of intracranial hemorrhage?death and severe disability;Favorable outcome rates (MRS modified Rankin Scale 0-1); | — |
Countries
China
Contacts
Wuhan Fourth Hospital