Stroke
Conditions
Interventions
Experimental group:Routine intervention + external diaphragm pacemaker + position management
control group:Routine intervention + postural management
Sponsors
The First Affiliated Hospital of Jishou University
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for severe stroke in the 2025 "Chinese Guidelines for the Management of Severe Stroke" 2. Age 20-70 years old 3. Diagnosis of first acute ischemic or hemorrhagic stroke by CT or MRI (onset time = 48 hours, and met the screening criteria of autonomous breathing test (conscious, stable hemodynamics, oxygenation index >= 150mmHg, etc.) 5. Difficulty in withdrawing from the machine with clinical judgment (failure of the first autonomous breathing test or expected difficulty)
Exclusion criteria
Exclusion criteria: 1. History of diaphragmatic paralysis or severe spinal cord injury 2. Severe hemodynamic instability (requiring a large amount of vasoactive drugs to maintain) 3. Severe abdominal distension, intra-abdominal hypertension, or recent abdominal surgery. 4. Severe chest deformities and multiple rib fractures with flail chest or skin diseases, unable to tolerate PM. 5. implantation of pacemakers or other electrical stimulation devices. 6. Neck and chest skin damage/burns/infections, unable to stick electrodes. 7. Expected survival = 2), bronchitis). 9. The patient or legal representative refuses to be randomized or is unable to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weaning Success Rate;diaphragm thickness; | — |
Secondary
| Measure | Time frame |
|---|---|
| diaphragmatic thickening;bedside heart rate variability;Incidence of respirator-associated pneumonia (VAP);Total mechanical ventilation time;arterial partial pressure of oxygen;arterial carbon dioxide partial pressure;28-Day mortality rate; | — |
Countries
China
Contacts
Public ContactShunyong Peng
The First Affiliated Hospital of Jishou University
Outcome results
None listed