A Preliminary Study on Real-Time fMRI Neurofeedback Based on Self-Compassion Strategies for Adolescents with Depression

Cognitive neural mechanisms of abnormal self-processing in adolescents with depression and suicidal ideation, and multi-level mechanism-oriented self-compassion interventions

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2600120561

Enrollment

Unknown

Registered

2026-03-17

Start date

2026-03-21

Completion date

Unknown

Last updated

2026-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depression

Interventions

Experimental group:Self-Compassion Techniques

Eligibility

Sex/Gender

All

Age

11 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1. Aged 11-18; 2. Right-handed; 3. Normal vision or corrected vision; 4. Has had suicidal thoughts in the past month or a suicide attempt in the past year; 5. Meets the diagnostic criteria for depression.

Exclusion criteria

Exclusion criteria: 1. Bipolar disorder; 2. Anxiety disorders with depression; 3. Current or previous psychotic disorders; 4. Current or history of organic brain diseases or neurological disorders; 5. Cochlear implants, pacemakers, intracranial implants or metal, and other MRI contraindications; 6. Neurological trauma, autism, developmental delays, visual and hearing problems, and substance dependence; 7. History of moderate to severe traumatic brain injury; 8. Electroconvulsive therapy received in the past month.

Design outcomes

Primary

Measure	Time frame
Montgomery-?sberg Depression Rating Scale (MADRS);Hamilton Anxiety Rating Scale (HAM-A);Columbia-Suicide Severity Rating Scale (C-SSRS);Self-Compassion Scale (SCS) ;Chinese Version of the Self-Disgust Scale (SDS-C);Beck Hopelessness Scale(BHS);Collaborative Assessment and Management of Suicidality - Suicide Status Form - Adult Version (CAMS SSF-A) ;Positive and Negative Affect Schedule;Patient Health Questionnaire (PHQ-9) ;Ruminative Responses Scale - Chinese Version;Short Form 36 Health Survey Questionnaire;Snaith-Hamilton Pleasure Scale;Satisfaction with Life Scale;Toronto Alexios Scale-20;Pittsburgh Sleep Quality Index;	—

Measure

Time frame

Montgomery-?sberg Depression Rating Scale (MADRS);Hamilton Anxiety Rating Scale (HAM-A);Columbia-Suicide Severity Rating Scale (C-SSRS);Self-Compassion Scale (SCS) ;Chinese Version of the Self-Disgust Scale (SDS-C);Beck Hopelessness Scale(BHS);Collaborative Assessment and Management of Suicidality - Suicide Status Form - Adult Version (CAMS SSF-A) ;Positive and Negative Affect Schedule;Patient Health Questionnaire (PHQ-9) ;Ruminative Responses Scale - Chinese Version;Short Form 36 Health Survey Questionnaire;Snaith-Hamilton Pleasure Scale;Satisfaction with Life Scale;Toronto Alexios Scale-20;Pittsburgh Sleep Quality Index;

—

Countries

China

Contacts

Public ContactLiu Guanmin/Zhang Bin

Tianjin Anding Hospital Institute of Applied Psychology, School of Medicine, Tianjin University

liugm@tju.edu.cn+86 150 0108 1283

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 3, 2026