Breast cancer
Conditions
Interventions
Gold Standard:Pathological findings of surgical excision or puncture
Index test:Benign and malignant, molecular subtypes
Sponsors
The 960th Hospital of the PLA Joint Logistics Support Force
Eligibility
Sex/Gender
Female
Age
28 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. 1.5T/3.0T MRI plain scan and enhanced examination of the breast were performed before the operation or before puncture. All sequence examinations were completed and the image quality was qualified. For patients who receive neoadjuvant chemotherapy after puncture, the MRI results during chemotherapy and before the surgery after the end of chemotherapy should also be included. 2. After coarse needle puncture biopsy or surgical treatment, there are pathological puncture results or surgical pathological results, with complete immunohistochemical results, obtaining histological classification, histological grade, molecular typing, Miller & Payne grade after neoadjuvant chemotherapy, etc. 3. There are complete clinical data, including menstrual status, height, body weight, past medical history, surgical history, etc. For breast cancer patients undergoing surgical treatment, ipsilateral axillary sentinel lymph node biopsy or axillary lymph node dissection has been performed to obtain information on whether there is metastasis in the axillary lymph nodes and the number of metastases.
Exclusion criteria
Exclusion criteria: 1. Those with contraindications for MRI examination; 2. Those who are unable to undergo gadopentine meglumine (Gd-DTPA) enhanced examination; 3. Patients with recurrence after breast-conserving surgery for breast cancer; 4. Patients who have undergone surgery on the affected breast; 5. Non-mass breast lesions; 6. Suffering from other malignant tumor diseases or hematological diseases at the same time; 7. Those with poor image quality or inability to delineate the ROI of the lesion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area under the operating characteristic curve of the subject; | — |
Secondary
| Measure | Time frame |
|---|---|
| Accuracy;Sensitivity;Specificity; | — |
Countries
China
Contacts
Public ContactMa Yunhan
The 960th Hospital of the PLA Joint Logistics Support Force, 25 Normal Road, Tianqiao District, Jinan City, Shandong Province, China
Outcome results
None listed