Postoperative pain in the oropharyngeal region surgery
Conditions
Interventions
experimental group:Bupivacaine liposome local infiltration + intravenous analgesia
Sponsors
Chengdu Seventh People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Schedule an oral cavity surgery for the future.; 2. American Society of Anesthesiologists ?- ?; 3. Age range: 18 - 65 years old. Gender: Open to all; 4. 18-35kg/m^2.
Exclusion criteria
Exclusion criteria: 1. History of allergy to local anesthetics, opioids, and non-steroidal drugs, history of abuse and addiction to analgesic drugs; 2. Preoperative oropharyngeal pain and sensory disorders caused by various reasons; 3. Current severe heart and lung diseases, liver and kidney dysfunction, bleeding disorders and coagulation dysfunction; 4. History of peptic ulcers; 5. Communication disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cumulative dosage of opioid drugs within 72 hours after surgery (in terms of morphine equivalent mg); | — |
Secondary
| Measure | Time frame |
|---|---|
| Discharge quality of recovery score QoR-15;Postoperative hospital stay;The incidence of chronic postoperative pain;Sleep quality 72 hours after surgery;Incidence of adverse reactions and complications;The time of the first remedial analgesia after surgery, and the number of remedial analgesia sessions within 72 hours;The incidence rates of moderate to severe pain during rest and during swallowing at 24 hours, 48 hours, and 72 hours after the operation;The area under the pain-time curve (AUC) at rest and during swallowing at 24 hours, 48 hours, and 72 hours after the operation;; | — |
Countries
China
Contacts
Public ContactLei Bao
Chengdu Seventh People's Hospital
Outcome results
None listed