Painless gastrointestinal endoscopy
Conditions
Interventions
O1:Normal saline + cyclopofol
O2:5 µ g/kg of oxelidin + cyclopofol
O3:10 µ g/kg of oxelidin + cyclopofol
O4:15 µ g/kg of oxelidin + cyclopofol
O5:20 µ g/kg of oxelidin + cyclopofol
O6:25 µ g/kg of oxelidin + cyclopofol
O7:30 µ g/kg of oxelidin + cyclopofol
Sponsors
Hainan Provincial People's Hospital (Affiliated Hospital of Hainan Medical University)
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. 105 elderly patients scheduled for painless gastroscopy; 2. ASA grades I to III; 3. Age > 65 years old; 4. BMI 15 - 28 kg/m^2.
Exclusion criteria
Exclusion criteria: 1. Have a history of highly reactive airway diseases, have acute upper respiratory tract infections, have a high risk of aspiration, have esophageal stenosis or cardiosphincter obstruction, have acute upper gastrointestinal bleeding, have hearing impairment; 2. Have severe lesions in important organs such as heart, liver, lungs and kidneys, as well as water and electrolyte disorders, have a history of mental illness, have a long-term history of taking psychotropic and sedative-hypnotic drugs, have sleep apnea syndrome, and have a history of drug allergies; 3. Have participated in other clinical trials as subjects within the past 3 months and have refused to undergo this clinical research experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intolerance response indicators (choking cough reflex, swallowing reflex, retching reflex, limb movement response); | — |
Secondary
| Measure | Time frame |
|---|---|
| Bispectral index monitoring;Gastroscopy examination time ;Heart rate;Postoperative recovery time;Mean arterial pressure; | — |
Countries
China
Contacts
Public ContactNa Li
Hainan Provincial People's Hospital (Affiliated Hospital of Hainan Medical University)
Outcome results
None listed