Hepatocellular carcinoma
Conditions
Interventions
Surgical treatment group of hepatocellular carcinoma patients:NA
Sponsors
The second Affiliated Hospital of Kunming Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients admitted with clinical and postoperative pathological diagnosis of hepatocellular carcinoma; 2. In patients who had undergone surgical resection, the resection grade was R0 resection (no macroscopic cancer embolus was seen in hepatic vein, portal vein, biliary duct, and inferior vena cava; No invasion of adjacent organs, no hilar lymph nodes or distant metastasis; The liver incisal margin was more than 1 cm from the tumor boundary. If the incision margin is less than 1 cm, the histological examination of the resected liver section shows no residual tumor cells, that is, the incision margin is negative. 3. Patients who do not have malignant tumors at other sites; 4. Patients with viral hepatitis who have received regular antiviral therapy; 5. Patients who did not receive TACE, SRRT, or systemic therapy before surgery; 6. No other adverse prognostic diseases, such as malignant hypertension, cardiovascular accidents, etc.
Exclusion criteria
Exclusion criteria: 1. Postoperative pathological diagnosis of non-hepatocellular carcinoma tumors, such as bile duct cell carcinoma, adenocarcinoma, etc; 2. Patients who could only be treated conservatively and those who died during perioperative period were assessed; 3. Patients with other high-risk diseases and malignant tumors in other parts of the body; 4. Patients who lost follow-up for multiple reasons; 5. Patients who had received TACE, SRRT, systemic therapy before surgery; 6. Combined with other poor prognosis diseases, such as malignant hypertension, cardiovascular accidents and so on.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ki-67;Patient disease-free survival and overall survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Preoperative imaging findings;AFP, liver and kidney function, and hepatitis immunity; | — |
Countries
China
Contacts
Public ContactWenxiang Jin
The second Affiliated Hospital of Kunming Medical University
Outcome results
None listed