Congenital heart disease ,insufficient heart function
Conditions
Interventions
Experimental Group A:On the basis of conventional inotropic therapy, levosimendan at a maintenance dose of 0.2 ug/kg/min was administered for 24 hours.
Control Group B:Clinical routine basic cardiotonic drug therapy (such as dopamine, epinephrine, norepinephrine, milrinone, etc.). Then normal saline was given to simulate the infusion rate of levosime
Sponsors
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
No minimum to 3 Years
Inclusion criteria
Inclusion criteria: 1. Knowing consent of parents or legal representatives; age 20 points.
Exclusion criteria
Exclusion criteria: 1.Severe arrhythmia; 2. Children with postoperative active bleeding; 3.Children with single ventricular physiological structure; 4.Those who are allergic to Zuoxin Mengdan and its drug components or are contraindicated; 5. The subject has any other major diagnosis or disease, and the investigator believes that these diagnosis or disease will affect the safety of the subject or the integrity of the study data; 6.The clinical data of the child is missing or missing follow-up;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vital signs (include heart rate, blood pressure, central venous pressure);Central venous oxygen saturation, blood lactate, blood type B brain natriuretic peptide level; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ejection Fraction,Tricuspid Annular Plane Systolic Excursion,Fractional Area Change,Ratio of Early Mitral Inflow Velocity to Mitral Annular Early Diastolic Velocity; | — |
Countries
China
Contacts
Public ContactChunxiang Li
Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed