Background and Scientific Rationale for Developing a Precision Diagnosis and Treatment System for Esophageal Squamous Cell Carcinoma Based on Oral Microbiome and AI-Assisted Emotion Recognition

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2600120487

Enrollment

Unknown

Registered

2026-03-16

Start date

2026-03-19

Completion date

Unknown

Last updated

2026-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal Squamous Cell Carcinoma

Interventions

Case group:None

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Aged >= 18 years; non-vulnerable groups (e.g., pregnant women, disabled individuals). 2.Histopathologically confirmed as esophageal squamous cell carcinoma (ESCC). 3.No prior history of cancer-related treatment.

Exclusion criteria

Exclusion criteria: 1.Patients with obvious oral inflammation. 2.A history of bacterial or viral infections involving the tonsils, salivary glands, or pharynx within 1 month prior to sampling. 3.Received periodontal therapy within 3 months prior to sampling. 4.Underwent general anesthesia surgery, radiotherapy, or chemotherapy within the past 6 months. 5.Complicated with other malignant tumors besides ESCC. 6.Received Helicobacter pylori eradication therapy within 4 weeks. 7.A history of facial aesthetic injections (e.g., botulinum toxin, hyaluronic acid, thread lifting) or craniomaxillofacial bone surgery.

Design outcomes

Primary

Measure	Time frame
Treatment Response;	—

Countries

China

Contacts

Public ContactBingwen Zou

West China Hospital of Sichuan University

zoubingwen81@163.com+86 28 85421479

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 3, 2026