Recurrent Spontaneous Abortion
Conditions
Interventions
Recurrent spontaneous abortion:None
Without experienced spontaneous abortion:None
Sponsors
Affiliated hangzhou first people's hospital, zhejiang university school of medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 48 Years
Inclusion criteria
Inclusion criteria: 1.Experimental group: Women of child - bearing age (18 - 48 years old); 2.Experimental group: Experienced two or more consecutive spontaneous abortions (including biochemical pregnancies) with the same sexual partner; 3.Experimental group: Able to provide complete clinical history information; 4.Experimental group: Willing to cooperate with blood sampling and sample retention; 5.Experimental group: Voluntarily participate in this study and sign the informed consent form; 6.Control group: Women of childbearing age (aged 18 to 48) who have not experienced a spontaneous abortion;
Exclusion criteria
Exclusion criteria: 1.Abnormal chromosomal karyotype of the couple; 2.Complicated with a certain malignant tumor disease; 3.The patient or their authorized person is unwilling to sign the written informed consent form or comply with the research protocol; 4.Suffering from other major diseases or being in the population with infectious diseases (such as HIV, etc.);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The characteristics of MN-DNA; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood routine indicators;Indicators related to maternal immunity, endocrine function, etc.; | — |
Countries
China
Contacts
Public ContactJianmei Xia
Affiliated hangzhou first people's hospital, zhejiang university school of medicine
Outcome results
None listed