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Risk of Complications in Intrapartum Cesarean Delivery: An Attribution Analysis of Labor Trial Effect and Pre-Existing Pathological Factors

Risk of Complications in Intrapartum Cesarean Delivery: An Attribution Analysis of Labor Trial Effect and Pre-Existing Pathological Factors

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600120461
Enrollment
Unknown
Registered
2026-03-16
Start date
2026-04-03
Completion date
Unknown
Last updated
2026-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intrapartum cesarean

Interventions

Sponsors

The international peace maternity and child health hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1.Singleton primiparous women at =37 weeks of gestation who underwent cesarean delivery.

Exclusion criteria

Exclusion criteria: 1. Maternal factors Severe pelvic deformity resulting in absolute cephalopelvic disproportion (anterior-posterior diameter of the pelvic inlet =8 cm), active bleeding from uterine rupture, active genital herpes lesions obstructing the birth canal, invasive cervical cancer (clinical stage =IIB requiring immediate pregnancy termination and radiotherapy), uncontrollable massive obstetric hemorrhage (ineffective uterotonics with blood loss >1500 mL or sudden Hb decrease >3 g/dL), NYHA class III–IV cardiac dysfunction. 2.Fetal factors Transverse lie or shoulder presentation (regardless of gestational age), mentoposterior position (mechanical obstruction due to face presentation), compound presentation with irreducible umbilical cord prolapse and fetal heart rate 1500 mL), grade IV placental abruption (abruption area >50% complicated by DIC or uteroplacental apoplexy), rupture of vasa previa in velamentous insertion (vaginal bleeding plus sudden fetal heart rate deceleration), vasa previa (uncorrected position anterior to the presenting part). 4.Special infectious and medical contraindications Uncontrolled HIV infection (viral load >1000 copies/mL without standard antiretroviral therapy), active tuberculous meningitis (to avoid brain herniation caused by intracranial pressure fluctuations during labor), preeclampsia or severe preeclampsia complicated by organ injury (cerebrovascular accident, HELLP syndrome, or acute renal failure). 5.Women without pregnancy complications such as diabetes mellitus, hypertension, or thyroid disorders;without complications during labor induction including fetal distress (per FIGO cardiotocography criteria), intrapartum fever (=38°C), or premature rupture of membranes >24 hours;who underwent cesarean section only due to failed induction (ineffective uterine contractions or arrested cervical dilation).

Design outcomes

Primary

MeasureTime frame
Incidence of Postpartum Hemorrhage;

Secondary

MeasureTime frame
Neonatal outcomes: asphyxia, birth injuries, NICU admission rate and length of stay, perinatal mortality;Short-term Postoperative Complications;Prevention of Postpartum Hemorrhage and Usage of Postpartum Hemorrhage Rescue Measures;

Countries

China

Contacts

Public ContactSu Xiaoxia

The international peace maternity and child health hospital

709560380@qq.com+86 21 1234567

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 3, 2026