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Synthetic PET from CT improves precision diagnosis and treatment of lung cancer: a prospective, observational, multicenter study

Synthetic PET from CT improves precision diagnosis and treatment of lung cancer: a prospective, observational, multicenter study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600120459
Enrollment
Unknown
Registered
2026-03-16
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-small cell lung cancer

Interventions

Gold Standard:Pathological examination
Index test:Generate corresponding PET image based on CT image

Sponsors

Shanghai Pulmonary Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients with non-small cell lung cancer scheduled to undergo PET-CT and pathological examinations;

Exclusion criteria

Exclusion criteria: 1.History of other malignant tumours; 2.Image artefacts; 3.Without pathological diagnostic information; 4.Without paired CT and FDG-PET scan images;

Design outcomes

Primary

MeasureTime frame
Consistency metrics: PSNR, SSIM, MAE, NRMSE, RMSE, metabolic parameters (SUVmax, MTV, TLG);—

Secondary

MeasureTime frame
Diagnostic accuracy;negative predictive value;Area under the curve (AUC);Positive predictive value;Diagnostic sensitivity;Diagnostic specificity;—

Countries

China

Contacts

Public ContactChang Chen

Shanghai Pulmonary Hospital

changchenc@tongji.edu.cn+86 21 65115006

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Apr 3, 2026