Stroke
Conditions
Interventions
Experimental group:Undergo 'conventional rehabilitation (45 minutes) and gamified robot training (30 minutes)' once daily for 15 consecutive days
Control group:Receive 'conventional rehabilitation (75 minutes)' once daily for 15 consecutive days
Sponsors
First Affiliated Hospital of Xinjiang Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Age: 18-75 years old (inclusive), no gender restriction 2.Diagnostic criteria: Meet the diagnostic criteria for stroke, confirmed by cranial CT or MRI, first-time stroke or previous stroke without significant sequelae (modified Rankin Scale, mRS =13 7.Vital signs stable: blood pressure, heart rate, and other vital signs are stable 8.Informed consent: patient or legal representative signs a written informed consent form
Exclusion criteria
Exclusion criteria: 1.Cognitive function-related: Severe cognitive impairment (MoCA =26), no cognitive training needed; history of dementia or neurodegenerative diseases (Alzheimer's disease, Parkinson's disease, etc.). 2.Aphasia (including transcortical motor aphasia, sensory aphasia, mixed aphasia). 3.Upper limb function-related: Severe shoulder dislocation or subluxation (requiring reduction treatment); stage II-III shoulder-hand syndrome (severe pain and swelling); severe contracture deformity of the affected upper limb (passive joint range of motion =24 or Anxiety Scale HAMA >=29); schizophrenia or other severe mental disorders; history of drug or alcohol abuse. 7.Other diseases: Malignant tumors or expected life expectancy 3 times the upper limit of normal, creatinine >2 times the upper limit of normal); uncontrolled diabetes (fasting blood glucose >10 mmol/L or 2-hour postprandial blood glucose >16 mmol/L); hematologic diseases or coagulation disorders; active infection or fever. 8.Other conditions: Pregnant or breastfeeding women; currently participating in other clinical trials; received upper limb rehabilitation robot training within the past month; presence of pacemaker, metal implants, or other MRI contraindications (such as planned fMRI examination); other conditions deemed by the investigator unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Assessment for Upper Extremity Motor Function (FMA-UE);Montreal Cognitive Assessment (MoCA); | — |
Secondary
| Measure | Time frame |
|---|---|
| Brunnstrom Stages;Seven-stage grading scale for upper limb recovery after hemiplegia;Hemiplegic Hand Function Assessment Scale;Electromyography;Action Research Arm Test (ARAT);Surface electromyography (sEMG) parameters;Barthel Index (ADL Assessment);Barthel Index;Neurobehavioral Cognitive Status Examination (NCSE);Brain Function MRI (fMRI);Electroencephalogram;fNIR;Self-Rating Depression Scale (SDS);Generalized Anxiety Disorder Scale (GAD-7); | — |
Countries
China
Contacts
Public ContactGuohua Zhu
First Affiliated Hospital of Xinjiang Medical University
Outcome results
None listed