Postoperative Pain
Conditions
Interventions
Intervention group:Intrathecal morphine
Sponsors
Zhengzhou Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Voluntarily participate in this trial, be able to understand the procedures and methods of this study, strictly abide by the clinical trial protocol to complete this trial, and voluntarily sign the informed consent; 2. Subjects scheduled for elective major laparoscopic abdominal surgery under general anesthesia (elective laparoscopic or laparoscopic-assisted abdominal surgery with an expected operation time of 2 hours or more); 3. Age >=18 years old; 4. American Society of Anesthesiologists (ASA) grade ?-?.
Exclusion criteria
Exclusion criteria: 1. Inability to complete the pain score or Quality of Recovery Questionnaire (QoR-15); 2. A history of chronic pain and opioid use; 3. Lactating or pregnant women; 4. Contraindications of intraspinal anesthesia; 5. Patients with previous lower limb neurological deficits or obvious respiratory diseases; 6. Allergy to study drugs (morphine, non-steroidal anti-inflammatory drugs).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-15 score on postoperative day 1; | — |
Secondary
| Measure | Time frame |
|---|---|
| QoR-15 scores on postoperative days 2 and 3;Time to first ambulation after surgery;Incidence of pruritus;Incidence of nausea or vomiting;Patient satisfaction;Postoperative length of hospital stay; | — |
Countries
China
Contacts
Public ContactShanshan Zuo
Zhengzhou Central Hospital
Outcome results
None listed