anxiety state in patients with acute coronary syndrome
Conditions
Interventions
Trial Group:Conventional Western medicine combined with electroacupuncture (acupoints: Neiguan, Lingdao, Shenmen, Yintang, Shenting, Baihui, Juque, Zusanli, Sanyinjiao, Xuehai, etc.
continuous wave electroacupuncture, frequency 2Hz, needle retention 30 minutes
started on day 1 post-PCI, once daily for 6 days)
Control Group:Conventional Western medicine treatment (antiplatelet, anticoagulant, lipid-lowering, beta-blockers, RAAS blockers, nitrates, calcium channel blockers, etc.
not strictly standardized)
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
36 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for ACS and successfully underwent PCI at our hospital, then transferred to CCU. 2. Age between 36-80 years (inclusive of critical values), gender unrestricted. 3. Killip heart function classification is class I-III. 4. Meet the diagnostic criteria for anxiety state, with mild to moderate anxiety state, i.e., GAD-7 score between 5-14 points (inclusive of critical values). 5. No prior history of anxiety state, i.e., the primary caregiver filled out the informant version of Hospital Anxiety and Depression Scale (HADS), anxiety subscale (HADS-A) score <=7 points. 6. Voluntarily participate in this study and sign the informed consent form. Participants who meet all 6 of the above criteria can be included in this clinical trial.
Exclusion criteria
Exclusion criteria: 1. Those who experienced severe complications after PCI, such as acute coronary artery occlusion, no-reflow of the coronary artery, coronary artery rupture or perforation, perioperative myocardial infarction, etc. 2. Those with severe functional impairment of major organs or acute infectious diseases, such as respiratory failure, cerebral hemorrhage, cerebral infarction, liver failure, kidney failure, etc. 3. Those with severe intellectual disability and unable to cooperate with scale assessment. 4. Those with damaged or infected skin at the acupuncture site and not suitable for acupuncture, or those who cannot tolerate conventional antiplatelet, lipid-lowering, etc. drugs. 5. Pregnant women, lactating women, or those planning to conceive in the near future. 6. Those participating in another clinical study simultaneously. Any of the above conditions will disqualify a participant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total effective rate of clinical efficacy; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM syndrome score;Myocardial injury markers;Inflammatory response markers;Central nervous system injury markers;Heart rate variability (HRV) indices;Left ventricular ejection fraction (LVEF);Incidence of major adverse cardiovascular events (MACE); | — |
Countries
China
Contacts
Public ContactLi Jing
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed