None
Conditions
Interventions
Dexmedetomidine Nasal Spray Group:Dexmedetomidine nasal spray administered prior to general anesthesia
Normal Saline Group:Intranasal administration of an equal volume of normal saline Prior to General Anesthesia
Sponsors
Sir Run Run Shaw Hospital Affiliated to Nanjing Medical University
Eligibility
Sex/Gender
All
Age
2 Years to 6 Years
Inclusion criteria
Inclusion criteria: 1.Scheduled for elective endoscopic intestinal tube placement; 2.ASA physical status I-II; 3.Aged 2 to 6 years; 4.Legal guardian has provided fully informed consent.
Exclusion criteria
Exclusion criteria: 1.Allergy or contraindication to dexmedetomidine, esketamine, or propofol; 2.Presence of severe renal, hepatic, neurological, or cardiovascular diseases; 3.History or presence of conditions associated with increased intracranial pressure; 4.Current upper respiratory infection, tracheitis, bronchitis, or pulmonary infection, and/or an anticipated difficult airway; 5.Parent or legal guardian refusal to provide consent and participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anxiety Score;Induction Compliance;Parental Separation Anxiety Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative Hypotension;Bradycardia;Total Propofol Consumption;Emergence Time;Emergence Agitation ; | — |
Countries
China
Contacts
Public ContactLiao Yanxiang
Sir Run Run Shaw Hospital Affiliated to Nanjing Medical University
Outcome results
None listed