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Research on the Role of Pulmonary Microbiome in the Development of Chronic Respiratory Diseases and Clinical Intervention

Study on the Correlation between Immune Cell Changes in Chronic Respiratory Diseases and Lung Microecology

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600120417
Enrollment
Unknown
Registered
2026-03-13
Start date
2026-01-15
Completion date
Unknown
Last updated
2026-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma, Chronic Obstructive Pulmonary Disease, and Bronchiectasis

Interventions

Bronchiectasis Group:N/A
COPD Group:N/A
Asthma Group:N/A

Sponsors

The second affiliated hospital of Zhejiang University school of medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Chronic Obstructive Pulmonary Disease (COPD): (1) Age >=40 years; (2) History of smoking (pack-years >=10) or exposure to biomass fuels or occupational hazards; (3) Post-bronchodilator FEV1/FVC ratio =6 months; (3) Participants voluntarily enroll in this study and sign a written informed consent form.

Exclusion criteria

Exclusion criteria: HIV patients or individuals with other immunodeficiency conditions (including neutropenia, hematologic malignancies, solid tumors undergoing chemotherapy or radiotherapy, organ transplantation, long-term corticosteroid or cytokine antagonist therapy);pregnant or lactating women; positive results for four infectious diseases (including hepatitis B, syphilis, etc.).

Design outcomes

Primary

MeasureTime frame
Pulmonary Microorganisms;—

Countries

China

Contacts

Public ContactFeng Xu

The second affiliated hospital of Zhejiang University school of medicine

xufeng99@zju.edu.cn+86 571 8971 3742

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 20, 2026