Postoperative complications of thoracic surgery
Conditions
Interventions
Experimental group:The intubation method of laryngeal mask airway combined with bronchial blocker
Control group:Double-lumen endotracheal intubation
Sponsors
Binzhou Medical University Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age = 65 years, regardless of gender; 2. Scheduled for elective thoracoscopic surgery (lobectomy, segmentectomy); 3. ASA physical status class II–III; 4. Normal preoperative cognitive function (MMSE score = 26); 5. Written informed consent obtained from the patient and/or legal representative.
Exclusion criteria
Exclusion criteria: 1. Anticipated difficult airway (modified Mallampati grade IV, mouth opening 35 kg/m²); 3. History of neurological diseases such as cerebrovascular disease, dementia, Parkinson’s disease, etc.; 4. Severe uncontrolled gastroesophageal reflux disease or high risk of aspiration; 5. Coagulation disorders or history of immunosuppressant use; 6. Preoperative active pulmonary infection, severe COPD (FEV1% predicted < 50%), or pulmonary hypertension; 7. History of previous ipsilateral thoracic surgery or expected severe pleural adhesions; 8. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite incidence of postoperative pulmonary complications (PPCs) within 7 days postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| BALF analysis: total cell count, percentage of neutrophils, concentrations of IL-6 and IL-8;Plasma biomarkers: detection of sRAGE and SP-D concentrations (specific biomarkers reflecting alveolar epithelial cell damage); | — |
Countries
China
Contacts
Public ContactQuanyi Zhang
Department of Anesthesiology, Binzhou Medical University Hospital
Outcome results
None listed