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The Effects of ImPACT Intervention on Core Symptom Improvement in Children with Autism and the Underlying Neural Mechanisms

The Effects of ImPACT Intervention on Core Symptom Improvement in Children with Autism and the Underlying Neural Mechanisms

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600120388
Enrollment
Unknown
Registered
2026-03-13
Start date
2025-01-04
Completion date
Unknown
Last updated
2026-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autism Spectrum Disorder

Interventions

ImPACT Group:Naturalistic Developmental Behavior Intervention (ImPACT): Parent training and implementation based on Applied Behavior Analysis (ABA), with one weekly hospital session (group teaching +
Waitlist Control Group:No immediate receipt of ImPACT intervention
only baseline assessment, follow-up assessments, and inquiry about supplementary intervention interest at 3-month follow-up.

Sponsors

Institute of Brain and Psychological Science, Sichuan Normal University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 6 Years

Inclusion criteria

Inclusion criteria: 1. Age: 2 to 6 years old. 2. Diagnosed with or suspected to have Autism Spectrum Disorder (ASD) by a clinician according to the DSM-5 criteria. 3. Meeting the ASD classification on the Autism Diagnostic Observation Schedule, Second Edition (ADOS-2). 4. Willing to receive early intervention and able to achieve an intensity of approximately 20 hours per week.

Exclusion criteria

Exclusion criteria: 1. Presence of other psychiatric or neurological disorders. 2. Previous use of psychotropic medications or receipt of electroconvulsive therapy. 3. History of traumatic brain injury. 4. earing or visual impairments. 5. Motor dysfunction. 6. Having undergone TMS intervention or oxytocin-based therapy within the preceding three months.

Design outcomes

Primary

MeasureTime frame
Functional magnetic resonance brain blood oxygen level-dependent signals;The score of the ADOS-2 Diagnostic Observation Scale for Autism;

Secondary

MeasureTime frame
The score of the second Edition of the Adaptive Behavior Rating Scale ABAS2 questionnaire;The score of the second edition of the Social Response Scale SRS2 questionnaire;Peabody Picture Vocabulary Test - Chinese Version;Griffiths Development Scales;Children’s Sleep Habits Questionnaire;

Countries

China

Contacts

Public ContactKou Juan

Institute of Brain and Psychological Science, Sichuan Normal University

koujuan@sicnu.edu.cn+86 187 8223 8905

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 20, 2026