Traumatic spinal cord injury
Conditions
Interventions
Experimental group:Bony Deompression and Dural Decompression
Control group:Bony decompression
Sponsors
Xuanwu Hospital Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age range: 18 - 80 years old, gender not restricted; 2. After clinical assessment including medical history, physical examination, and auxiliary tests, diagnosed as patients with cervical or thoracic (C2-T12) spinal cord injury caused by trauma; 3. According to the International Standard for Neurological Classification of Spinal Cord Injury (ISNCSCI), classified as grades A, B, or C based on the ASIA impairment scale (AIS); 4. Surgery was performed within 72 hours after traumatic spinal cord injury; 5. Preoperative MRI T2-weighted sequence indicated that there was no cerebrospinal fluid signal between the spinal cord and the dura mater in at least one segment; 6. Generally in good health condition, with an expected lifespan of >= 12 months; 7. The subjects voluntarily participated in this study, signed the informed consent form, had good compliance, and cooperated with follow-up.
Exclusion criteria
Exclusion criteria: 1. Combined with other severe injuries (such as brain injury, liver and spleen rupture, etc.) or underlying diseases unsuitable for surgical treatment (judged by the principal investigator); 2. Transverse spinal cord injury; 3. Spinal cord gunshot or sharp instrument injury; 4. Rupture of the dura mater caused by traumatic spinal cord injury; 5. Other diseases (including mental disorders) that may impede accurate medical and neurological assessment (judged by the principal investigator)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The change value of the motor score of the American Spinal Injury Association; | — |
Secondary
| Measure | Time frame |
|---|---|
| American Spinal Injury Association Motor Function Score;American Spinal Injury Association Sensory Score;American Spinal Injury Association Classification;Spinal Cord Injury Walking Index;Spinal Cord Injury Independence Scale Score;Quality of Life Scale Score;Degree of pain;Neurogenic bladder symptom score;Neurogenic intestinal dysfunction score;Adverse event; | — |
Countries
China
Contacts
Public ContactWanru Duan
Capital Medical University Xuanwu Hospital
Outcome results
None listed