stroke
Conditions
Interventions
Experimental group:Bilateral Transcutaneous Auricular Vagus Nerve Stimulation + Conventional Rehabilitation
Bilateral Transcutaneous Auricular Vagus Nerve Stimulation: The bilateral synchronous auric
Control group:Sham Stimulation of Bilateral Transcutaneous Auricular Vagus Nerve Stimulation + Conventional Rehabilitation
Sham Stimulation of Bilateral Transcutaneous Auricular Vagus Nerve Stimulati
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. First-ever stroke, with unilateral lesions, or a history of previous stroke but without significant neurological deficits; 2. Patients aged >= 40 years and 21, and ability to cooperate with assessments and training; 6. Patients and their family members sign the informed consent form and voluntarily participate in this study.
Exclusion criteria
Exclusion criteria: 1. Previous history of vagus nerve surgery; 2. Use of a cardiac pacemaker or other implantable electronic devices; 3. Presence of severe cardiovascular disease, or pulmonary, hepatic, or renal insufficiency; 4. Presence of other causes of upper limb dysfunction unrelated to stroke; 5. Use of psychiatric medications, or a history of mental illness or epilepsy; 6. Symptomatic bradycardia (heart rate < 60 bpm); 7. Women who are pregnant, breastfeeding, or planning pregnancy in the near future.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hand dexterity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serial Reaction Time ;Upper limb motor function;Fugl-Meyer Assessment - Upper Extremity;EEG Data; | — |
Countries
China
Contacts
Public ContactXu Dongsheng
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed