pathological scars
Conditions
Interventions
the punch-PDT Group:In this group, after local infiltration anesthesia with lidocaine injection, a micro ring drill with an adjustable rotation speed and an inner diameter of 0.8–1 mm was selected. Th
the PDT Group:Apply a 10% ALA wet compress to the affected skin area
seal the lesion and shield it from light for 3 hours. Subsequently, irradiate the scar with red light at an output power of 80–100 mW/cm2 and a total irradiation energy of 100 J/cm2.
the Betamethasone Injection Group:In this group, We use a 2.5ml syringe to extract compound betamethasone and lidocaine injection 1:1, mix and shake well, inject the needle from one end of the bottom
Sponsors
The 907th Hospital of the Chinese People's Liberation Army Joint Logistics Support Force
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Subjects aged between 18 and 60 years; 2. Diagnosed with hypertrophic scars or keloids by a dermatologist according to the diagnostic criteria of the 2nd Edition of Clinical Dermatology in China; 3. Willing to sign an informed consent form and have reasonable expectations.
Exclusion criteria
Exclusion criteria: 1. History of photosensitivity or documented allergy to porphyrin compounds; 2. Presence of severe systemic conditions such as coronary heart disease or severe hypertension; 3. Pregnant or lactating women, including women of childbearing potential planning pregnancy during this phase or not using effective contraception; 4. Blood-borne infectious diseases such as HIV or syphilis; 5. Localized severe bacterial infections or viral infections such as herpes simplex; 6. Scars treated within the past 3 months with systemic medications, injections, laser therapy, or surgery; 7. Other conditions or circumstances, as determined by the treating investigator, that may place the subject at significant risk, confound study results, or substantially interfere with the subject's ability to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Vancouver Scar Scale (VSS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse reactions; | — |
Countries
China
Contacts
Public ContactHu Cheng
The 907th Hospital of the Chinese People's Liberation Army Joint Logistics Support Force
Outcome results
None listed