Stroke
Conditions
Interventions
The sham stimulation group:tACS sham stimulation
Single-target group:Single-target tACS
Dual-target group:Dual-target tACS
Sponsors
Shanghai Seventh People's Hospital
Eligibility
Sex/Gender
All
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age: 45 - 75 years old, gender not restricted, normal vision or corrected vision; 2. Meets the diagnostic criteria of the "Combined Diagnosis Standards for Cerebral Infarction and Cerebral Hemorrhage (Trial)" in 2006, and has been confirmed by head CT or MRI examination; 3. Has cognitive dysfunction as assessed by MoCA-BJ (total score = 25 points); 4. Cognitive function was normal before the onset; 5. First episode; 6. Disease course = 3 months, stable condition, stable vital signs; 7. Can maintain a sitting position for 30 minutes or more independently; 8. Clear consciousness, no aphasia or hemispatial neglect, able to understand the content of the scale and cooperate with examinations and treatments; 9. Voluntarily sign the informed consent form and understand the research content.
Exclusion criteria
Exclusion criteria: 1. Patients with critical illness or whose acute condition has not yet stabilized; 2. Those with complete frontal lobe damage confirmed by CT or MRI; 3. Patients with bilateral brain damage; 4. Those meeting the diagnostic criteria for post-stroke depression as stipulated in the "Chinese Expert Consensus on Clinical Practice of Post-Stroke Depression" ; 5. Patients diagnosed with any other neurological disorder; 6. Patients with hearing loss, aphasia or severe cognitive impairment, making normal communication difficult; 7. Patients with severe cardiovascular or other serious health problems; 8. Patients unable to cooperate with the rehabilitation plan of this study; 9. Patients concurrently participating in other clinical trials; 10. Patients unable to understand or unable to sign the informed consent form; 11. Patients with any contraindications for tACS or EEG, such as having a pacemaker, cochlear implant, or metal implants in the brain; 12. Other situations deemed inappropriate for participation in this study by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MoCA-BJ Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Digital breadth ;Modified Bacterial Index;EEG-related data; | — |
Countries
China
Contacts
Public ContactXiaoming Yu
Shanghai Seventh People's Hospital (Seventh People's Hospital Affiliated to Shanghai University of Traditional Chinese Medicine)
Outcome results
None listed