Nasopharyngeal Carcinoma
Conditions
Interventions
Gold Standard:Nasopharyngeal biopsy
Index test:Detection of EBV-Related Antibody Markers Based on Chemiluminescence Method
Sponsors
Sun Yat-sen University Cancer Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Nasopharyngeal carcinoma (NPC) group 1.Cases initially diagnosed as Nasopharyngeal carcinoma through pathological examination; 2.No restrictions on age, gender or pathological stage; 3.No previous anti-tumor treatments such as surgery, chemotherapy, radiotherapy or immunotherapy have been received; 4.Primary tumors in other parts were ruled out through CT, MRI or PET-CT examinations combined with clinical symptoms; 5.Serum samples were collected before any clinical treatment was received, and the sample volume was no less than 600 µL; 6.The medical record information is complete and there is data from the last follow-up; Non-NPC control group: Follow-up for at least 2 years or more, with no clinical symptoms related to nasopharyngeal carcinoma, no solid tumors detected in chest CT scans, no history of other malignant tumors, and basic normal results in blood routine, blood biochemistry, and liver and kidney function tests.
Exclusion criteria
Exclusion criteria: 1.Concurrent other malignant tumors; 2.Have autoimmune system diseases; 3.The sample quality does not meet the operational requirements (such as improper sample collection, improper preservation, insufficient sample size, sample leakage, sample contamination, and abnormal sample). 4.Missing medical records;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity;Accuracy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive predictive value;Negative predictive value; | — |
Countries
China
Contacts
Public ContactQian Zhong
Sun Yat-sen University Cancer Center
Outcome results
None listed