Diabetic macular edema
Conditions
Interventions
Diabetic macular edema observation group:None
Sponsors
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old, gender not restricted, and signed informed consent; 2. Clinically diagnosed with DME; 3. Received Fasrelizumab treatment (loading period + T&E) and underwent follow-up and clinical assessment; 4. Before the initial injection, no any DME-related treatment was received; 5. There is a relatively complete assessment of DME disease.
Exclusion criteria
Exclusion criteria: 1. Patients who did not receive Fasrice antibody treatment as per the instructions; 2. Other exudative macular diseases, severe cataracts, etc.; 3. Other ocular diseases such as glaucoma and uveitis that affect the treatment plan; 4. Severe systemic diseases (advanced cancer, renal failure, etc.); 5. Poor OCTA imaging due to unclear refractive media, eye movement, etc.; 6. Previous history of intraocular surgery (such as vitrectomy surgery, etc.); 7. Those with 80% incomplete clinical records of injection, clinical assessment and follow-up within 12 months; 8. Those who had no OCT scan data at baseline and the last follow-up, or the OCT scan area centered on the fovea was not 6mm*6mm.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Subretinal fluid;Intraretinal fluid ;Hyperreflective foci;External limiting membranes;Ellipsoid zone ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammation cytokines; | — |
Countries
China
Contacts
Public ContactDong Wentao
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
Outcome results
None listed