Mental disorders
Conditions
Interventions
Cohort for depressive disorder:None
Cohort for bipolar disorder:None
Cohort for schizophrenia:None
Cohort for health control:None
Sponsors
Hangzhou Seventh People's Hospital
Eligibility
Sex/Gender
All
Age
8 Years to 60 Years
Inclusion criteria
Inclusion criteria: The schizophrenia group: 1. Age: 16.5-45 years old; 2. Nationality: Han; 3. Handedness: right-handed/mixed-handed; 4. No seizure or medication requirements; 5. Diagnosis: in line with the diagnostic criteria for schizophrenia in the American Diagnostic and Statistical Manual of Mental Disorders (DSM-5); 6. Intelligence level: Wechsler Intelligence Test >=70; 7. Voluntarily participate in this study and sign the informed consent form; 8. This attack is not obviously related to specific life events. The bipolar disorder group: 1. Age: 12-55 years old; 2. Nationality: Han; 3. Handedness: right-handed/mixed-handed; 4. No seizure or medication requirements; 5. Diagnosis: in line with the Diagnostic and Statistical Manual of Mental Disorders, Diagnostic criteria for bipolar disorder in DSM-5); 6. Intelligence level: Wechsler Intelligence Test >=70; 7. Voluntarily participate in this study and sign the informed consent form; 8. This attack is not obviously related to specific life events. The depression group: 1. Age: 14-60 years old; 2. Nationality: Han; 3. Handedness: right-handed/mixed-handed; 4. No seizure or medication requirements; 5. Diagnosis: in line with the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) diagnostic criteria for major depressive disorder; 6. Intelligence level: Wechsler Intelligence Test >=70; 7. Voluntarily participate in this study and sign the informed consent form; 8. This attack is not obviously related to specific life events.
Exclusion criteria
Exclusion criteria: The schizophrenia group: 1. Those with a history of head trauma; a history of blood transfusion; those with organic brain diseases, neurological diseases, and severe endocrine or metabolic diseases; 2. Those with other DSM-IV Axis I and II diseases (such as alcohol/substance-related disorders, mental retardation, etc.); 3. Those who are uncooperative or unable to complete the test effectively; 4. Those with fixed metal dentures, pacemakers or metal prosthetic implants; 5. Color blindness; 6. Being in the pregnancy and childbirth period within 1 year; 7. Having received electroconvulsive therapy within 6 months. The bipolar disorder group: 1. Those with a history of head trauma; a history of blood transfusion; those with organic brain diseases, neurological diseases, and severe endocrine or metabolic diseases; 2. Those with other DSM-IV Axis I and II diseases (such as alcohol/substance-related disorders, mental retardation, etc.) 3. Those who are uncooperative with the test or unable to complete it effectively; 4. Those with fixed metal dentures, pacemakers or metal prosthetic implants; 5. Color blindness; 6. Pregnant and childbirth within 1 year; 7. Patients who have received electroconvulsive treatment within 6 months. The depression group: 1. Those with a history of head trauma; a history of blood transfusion; those with organic brain diseases, neurological diseases, and severe endocrine or metabolic diseases; 2. Those with other DSM-IV Axis I and II diseases (such as alcohol/substance-related disorders, mental retardation, etc.) ; 3. Those who are not cooperative with the test or cannot complete it effectively; 4. Those with fixed metal dentures, pacemakers or metal prosthetic implants; 5. Color blindness; 6. Pregnant and childbirth within 1 year; 7. Patients who have received electroconvulsive treatment within 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Electroencephalogram; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton Depression Rating Scale,;DNA;Positive and Negative Syndrome Scale;Young Mania Rating Scale,; | — |
Countries
China
Contacts
Public ContactHaiteng Jiang
Hangzhou Seventh People's Hospital
Outcome results
None listed