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Evaluation of the effect of high-frequency jet ventilation combined with normal-frequency ventilation in preventing hypoxemia during thoracic surgery: A randomized controlled trial

Evaluation of the effect of high-frequency jet ventilation combined with normal-frequency ventilation in preventing hypoxemia during thoracic surgery: A randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600120279
Enrollment
Unknown
Registered
2026-03-11
Start date
2026-03-15
Completion date
Unknown
Last updated
2026-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pulmonary Complications

Interventions

High-frequency jet ventilation combined with conventional ventilation group:High-frequency jet ventilation superimposed with normal-frequency ventilation

Sponsors

Qilu Hospital (Qingdao) of Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients who voluntarily sign the informed consent form and are scheduled to undergo pulmonary surgery (wedge resection, segmentectomy, partial lobectomy, lobectomy, pneumonectomy) under general anesthesia.

Exclusion criteria

Exclusion criteria: 1. Patients who underwent emergency surgery; 2. were under 20 years old; 3. pregnant; 4. had quit smoking for less than two weeks; 5. had preoperative infections; 6. had severe preoperative cardiopulmonary diseases, and were judged by the researchers as unsuitable for participation in this trial.

Design outcomes

Primary

MeasureTime frame
The incidence of intraoperative hypoxemia;

Secondary

MeasureTime frame
Postoperative pulmonary complications, specifically including atelectasis, respiratory failure, pleural effusion, pneumonia, unplanned non-invasive or invasive ventilation, pulmonary edema, bronchospasm, and pneumothorax, with their respective incidence rates;Complications of combined respiratory conditions, including pulmonary embolism during hospitalization and acute respiratory distress syndrome.;Systemic complications, including systemic inflammatory response syndrome, sepsis, acute kidney injury, and wound infection;Vasopressors are required during the operation;Unplanned ICU admission;The call for the rapid response team;Length of stay in ICU;Length of hospital stay;In-hospital mortality rate;C reactive protein;Preoperative inflammatory factors;Postoperative inflammatory factors;The ratio of neutrophils to lymphocytes;

Countries

China

Contacts

Public ContactLi Jianjun

Qilu Hospital (Qingdao) of Shandong University

ljj9573@163.com+86 185 6181 1399

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 20, 2026