Ocular Herpes Simplex Virus (HSV) Disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who are willing to participate in the study and able to give informed consent; 2. Age 18 years or above; 3. Have had at least one episode of clinically confirmed ocular HSV disease (i.e., blepharitis,conjunctivitis, epithelial keratitis, stromal keratitis, or iritis) in one eye within the preceding 5 years; 4. Possess adequate cognitive ability to understand and complete the study questionnaires.
Exclusion criteria
Exclusion criteria: 1. Ocular diseases unrelated to HSV that significantly affect patients’ visual function and vision-related quality of life, including but not limited to advanced glaucoma, age-related macular degeneration, advanced cataract; 2. Active ocular infection of non-HSV etiology (e.g., bacterial, fungal, or acanthamoeba keratitis); 3. History of recent corneal or intraocular surgery within the preceding 6 months; 4. Documented history of ocular Varicella Zoster Virus disease; 5. Inability to reliably complete the study questionnaires (e.g., due to cognitive impairment).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The PROMs questionnaires score of patients with recurrent ocular HSV disease during the active and latent phases;The QoL questionnaires score of patients with recurrent ocular HSV disease during the active and latent phases; | — |
Countries
China
Contacts
Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong