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Quality of Life and Patient Reported Outcome Measures in Patients with Recurrent Ocular HSV Disease: A Prospective Cross-sectional Study

Quality of Life and Patient Reported Outcome Measures in Patients with Recurrent Ocular HSV Disease: A Prospective Cross-sectional Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600120278
Enrollment
Unknown
Registered
2026-03-11
Start date
2026-03-20
Completion date
Unknown
Last updated
2026-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ocular Herpes Simplex Virus (HSV) Disease

Interventions

Sponsors

Department of Ophthalmology and Visual Sciences, CUHK
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients who are willing to participate in the study and able to give informed consent; 2. Age 18 years or above; 3. Have had at least one episode of clinically confirmed ocular HSV disease (i.e., blepharitis,conjunctivitis, epithelial keratitis, stromal keratitis, or iritis) in one eye within the preceding 5 years; 4. Possess adequate cognitive ability to understand and complete the study questionnaires.

Exclusion criteria

Exclusion criteria: 1. Ocular diseases unrelated to HSV that significantly affect patients’ visual function and vision-related quality of life, including but not limited to advanced glaucoma, age-related macular degeneration, advanced cataract; 2. Active ocular infection of non-HSV etiology (e.g., bacterial, fungal, or acanthamoeba keratitis); 3. History of recent corneal or intraocular surgery within the preceding 6 months; 4. Documented history of ocular Varicella Zoster Virus disease; 5. Inability to reliably complete the study questionnaires (e.g., due to cognitive impairment).

Design outcomes

Primary

MeasureTime frame
The PROMs questionnaires score of patients with recurrent ocular HSV disease during the active and latent phases;The QoL questionnaires score of patients with recurrent ocular HSV disease during the active and latent phases;

Countries

China

Contacts

Public ContactJulia Yan Yu CHAN

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong

juliachan@cuhk.edu.hk+852 3943 5829

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 20, 2026