Impact of Bupivicaine Liposome Intercostal Nerve Block versus PCIA on the Incidence of chronic post-surgery pain in thoracic surgery patients: A Single-Center, Observational, Cohort Study

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2600120261

Enrollment

Unknown

Registered

2026-03-11

Start date

2025-10-22

Completion date

Unknown

Last updated

2026-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Post-surgery Pain

Interventions

Intraoperative Intercostal Nerve Block with Liposomal Bupivacaine Group:None

Postoperative PCIA Analgesia Group:None

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-75 years old ; 2. Undergoing elective uniportal video-assisted thoracoscopic surgery (VATS) for pulmonary surgery; 3. Receiving intraoperative intercostal nerve block with liposomal bupivacaine or postoperative patient-controlled intravenous analgesia (PCIA); 4. ASA classification of ?- ?.

Exclusion criteria

Exclusion criteria: 1. Patients whose surgical approach was altered during the procedure for any reason (e.g., conversion to thoracotomy); 2. Patients requiring invasive clinical interventions (e.g., thoracentesis) due to postoperative complications (e.g., pneumothorax); 3. Patients with preoperative analgesic dependence; 4. Patients with a history of chronic pain prior to surgery; 5. Patients undergoing reoperation within 3 months post-surgery; 6. Patients experiencing severe adverse events postoperatively, such as severe allergic reactions or mortality; 7. Patients with missing relevant clinical data; 8. Patients lost to follow-up within 3 months after surgery.

Design outcomes

Primary

Measure	Time frame
The incidence of Chronic Post-surgery Pain at 3 months after surgery.;The degree of Chronic Post-surgery Pain at 3 months after operation.;The nature of Chronic Post-surgery Pain at 3 months after operation;	—

Secondary

Measure	Time frame
Incidence of postoperative use of additional analgesics;NRS score at 24 and 72 hours after surgery;Incidence of adverse events within 24 and 72 hours postoperatively;The incidence of complication after surgery;the length of stay;the general expenses during hospitalization;The incidence of skin numbness in the operation area at 3 months after surgery;12-Item Short-Form Health Survey (SF-12) score at 3 months postoperatively;Time to first use of additional analgesic medication postoperatively;Types of rescue analgesia used postoperatively;	—

Measure

Time frame

Incidence of postoperative use of additional analgesics;NRS score at 24 and 72 hours after surgery;Incidence of adverse events within 24 and 72 hours postoperatively;The incidence of complication after surgery;the length of stay;the general expenses during hospitalization;The incidence of skin numbness in the operation area at 3 months after surgery;12-Item Short-Form Health Survey (SF-12) score at 3 months postoperatively;Time to first use of additional analgesic medication postoperatively;Types of rescue analgesia used postoperatively;

—

Countries

China

Contacts

Public ContactXiaohua Zou

Affiliated Hospital of Guizhou Medical University

562931613@qq.com+86 138 0941 6036

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 20, 2026