Hypercholesterolemia
Conditions
Interventions
The experimental group:Take 3g of krill oil soft capsules orally every day
The control group:Take 3g of soybean oil soft capsules orally every day
Sponsors
Qingdao University
Eligibility
Sex/Gender
All
Age
35 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age between 35-65 years old, regardless of gender or ethnicity; 2. Diagnosed with hypercholesterolemia, TC >= 5.2 mmol/L or LDL-C >= 3.4 mmol/L; 3. Weekly seafood intake should not exceed 200g; or have not taken n-3 polyunsaturated fatty acid supplements in the past 3 months; 4. Voluntarily participate and sign an informed consent form, cooperate to complete the questionnaire arranged by the researcher or accept telephone follow-up.
Exclusion criteria
Exclusion criteria: 1. Familial hyperlipidemia or triglyceride concentration >4.56mmol/L; 2. Suffering from any form of liver, kidney, and malignant tumors; 3. Individuals known to be allergic to seafood or research drugs (n-3 polyunsaturated fatty acids).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total cholesterol;Low density lipoprotein cholesterol;High density lipoprotein cholesterol;Triglyceride; | — |
Secondary
| Measure | Time frame |
|---|---|
| Height;Weight;Waist circumference;Hip circumference;Kidney function (creatinine, uric acid, urea nitrogen);Liver function (glutamic-pyruvic transaminase, glutamic oxalacetic transaminase);Blood glucose;Insulin;Hemoglobin;Red blood cell membrane phospholipid fatty acids; | — |
Countries
China
Contacts
Public ContactXiaofei Guo
School of Public Health, Qingdao University
Outcome results
None listed