Lung cancer
Conditions
Interventions
Gold Standard:Diagnosis of lung cancer: Histopathological examination after tumor puncture or surgical resection confirms lung cancer.
Index test:Single-omics analysis and multi-omics integrated analysis of exhaled breath condensate, including genomic, transcriptomic, proteomic, metabolomic, and microbiomic analyses.
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria for Lung Cancer Patients: 1. Age > 18 years; 2. Diagnosed with lung cancer or suspected lung cancer scheduled for surgical resection; 3. No prior history of malignant tumors; 4. No prior anti-tumor treatments such as radiotherapy, chemotherapy, or targeted therapy. Inclusion Criteria for Healthy Subjects: 1. Age > 18 years; 2. No space-occupying lesions found on chest CT; 3. No current or prior history of malignant tumors.
Exclusion criteria
Exclusion criteria: Exclusion Criteria for Lung Cancer Patients: 1. Inability to tolerate the collection procedure of exhaled breath condensate; 2. Presence or suspicion of active infection; 3. Abnormal liver or kidney function; 4. Postoperative pathology negates the diagnosis of lung cancer; 5. Insufficient volume of exhaled breath condensate collected or failure to pass quality inspection. Exclusion Criteria for Healthy Subjects: 1. Inability to tolerate the collection procedure of exhaled breath condensate; 2. Presence or suspicion of active infection; 3. Abnormal liver or kidney function; 4. Insufficient volume of exhaled breath condensate collected or failure to pass quality inspection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity;specificity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Multi omics abnormalities related to lung cancer; | — |
Countries
China
Contacts
Public ContactLi Xiangnan
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed