Anxiety, depression
Conditions
Interventions
experimental group:Prepare the esketamine injection into a concentration of 2.5mg/ml, and then administer it by infusion at a rate of 0.25mg/kg/h.
Control group:Administer 0.9% normal saline at a rate of 0.1 ml/kg/h through infusion.
Sponsors
Leshan People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old; 2. Planning for elective surgeries for thyroid cancer and breast cancer; 3. ASA classification: I-III grades; 4. Voluntary signing of the informed consent form.
Exclusion criteria
Exclusion criteria: 1. The preoperative diagnosis indicated a history of anxiety and depression disorders. 2. Patients allergic to esketamine; 3. Three months later, they will participate in other researches. 4. Intellectual or mental disorders, making it impossible to cooperate with the patient; 5. Patients who refuse to sign the consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence rates of postoperative anxiety and depression in both groups of patients within 72 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Compare the postoperative 48-hour quality of recovery (QoR-15) scores of the two groups;Compare the postoperative hospital stay days and the total cost from the start of the surgery to discharge for the two groups.;Compare the pain scores of the two groups at 48 hours and 72 hours after surgery; | — |
Countries
China
Contacts
Public ContactLin Hongyan
Leshan People's Hospital
Outcome results
None listed