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A Study on the Effects of Magnetic Shock Therapy on Symptom Improvement in Major Depressive Disorder and Changes in Cerebral Blood Flow and Brain Networks

A Study on the Effects of Magnetic Shock Therapy on Symptom Improvement in Major Depressive Disorder and Changes in Cerebral Blood Flow and Brain Networks

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600120235
Enrollment
Unknown
Registered
2026-03-11
Start date
2025-11-15
Completion date
Unknown
Last updated
2026-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depression

Interventions

50Hz group:50Hz magnetic seizure therapy
healthy control group:none
100Hz group:100Hz magnetic seizure therapy

Sponsors

The First Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Diagnosed with major depressive disorder according to DSM-5 criteria;18 to 60 years of age; 2.Fully comprehend the questionnaire's items and task requirements; 3.Voluntarily participate in this study and sign the relevant informed consent form; 4.No psychiatric medication taken in the 14 days prior to enrolment;

Exclusion criteria

Exclusion criteria: 1.Other mental disorders were identified via the SCID-5-CV interview. 2.History of neurological disorders, head trauma; cases with markedly elevated intracranial pressure; 3.Contraindications for MST: Individuals with ferromagnetic metallic foreign bodies or electronic devices implanted within the cranium; those with cardiac pacemakers or cardiac stents; and those with cochlear implants. 4.Individuals with unstable or severe medical conditions who cannot tolerate this therapy, or those who are pregnant or breastfeeding. 5.Individuals with anaesthetic allergies; smokers consuming =20 cigarettes per day;

Design outcomes

Primary

MeasureTime frame
HAMD Score Reduction Rate;

Secondary

MeasureTime frame
Clinical response rate;

Countries

China

Contacts

Public ContactWang Jincheng

The First Hospital of Hebei Medical University

wjc811125@126.com+86 186 3388 8776

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 20, 2026