Esting an "Artificial Pancreas" for Faster, Safer Recovery from Diabetic Crises ""

A Comparative Study on the Clinical Efficacy and Safety of Hybrid Closed-Loop Insulin Delivery Systems versus Standard Care in the Management of Diabetic Ketoacidosis

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2600120226

Enrollment

Unknown

Registered

2026-03-11

Start date

2026-03-17

Completion date

Unknown

Last updated

2026-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic Ketoacidosis

Interventions

Intervention Group (Hybrid Closed-Loop Insulin Delivery System):Hybrid Closed-Loop (HCL) Insulin Delivery System

Control Group (Conventional Insulin Pump Therapy, CSII Group):Conventional Insulin Pump Therapy

Eligibility

Sex/Gender

All

Age

2 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Patients meeting the diagnostic criteria for diabetic ketoacidosis; 2. Age 2 to 75 years old (inclusive); 3. Willing to sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Pregnant or lactating women; 2. Patients with severe cardiac, hepatic, or renal dysfunction; 3. Patients with concomitant malignancies or acute cardio-cerebrovascular diseases; 4. Patients with severe psychiatric disorders.

Design outcomes

Primary

Measure	Time frame
Time to Resolution of Acidosis ,Time in Range (TIR);	—

Secondary

Measure	Time frame
Mean blood glucose;Coefficient of variation of blood glucose;Blood glucose compliance rate;	—

Countries

China

Contacts

Public ContactWenqing Mo

Liuzhou Worker's Hospital

893465145@qq.com+86 772 3821561

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 20, 2026