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Research on an LLM-Based AI Guideline Assistant for Brain Tumor Treatment Response Assessment

Research on an AI Guideline Assistant for Brain Tumor Treatment Response Evaluation Based on Large Language Models

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600120219
Enrollment
Unknown
Registered
2026-03-11
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

brain glioma or metastatic tumor

Interventions

Traditional radiology report group:NA
AI report group:NA

Sponsors

Yuebei People’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. No restriction on gender; 2. Pathologically confirmed or follow-up verified diagnosis of brain glioma or metastasis; 3. Pathologically confirmed or follow-up verified diagnosis of brain glioma or metastasis; 4. Complete clinical history, imaging data, and necessary follow-up information, including detailed treatment records, medication information, neurological function scores (such as KPS or ECOG scores), and corticosteroid usage; 5. Complete baseline MRI examination before treatment and at least one follow-up MRI examination after treatment; 6. Time interval between the two MRI examinations complies with the assessment time window recommended by RANO guidelines; 7. Complete MRI scanning sequences, including at least axial contrast-enhanced T1-weighted imaging, T2-weighted imaging, and FLAIR sequences.

Exclusion criteria

Exclusion criteria: 1. Incomplete clinical or imaging data, unable to determine accurate treatment regimen, treatment timing, or neurological function status; 2. Poor MRI image quality with significant motion artifacts, susceptibility artifacts, or other factors affecting tumor measurement; 3. MRI scanning does not comply with RANO standards, including missing necessary contrast-enhanced sequences, slice thickness >5mm, or scanning parameters severely deviating from standards; 4. Concurrent other intracranial lesions (such as cerebrovascular lesions, infections, etc.) that may interfere with treatment response assessment; 5. Presence of severe systemic diseases or complications that may affect imaging interpretation; 6. Post-treatment non-tumor-related intracranial changes (such as radiation necrosis, hemorrhage, infarction, etc.) that are difficult to differentiate from tumor progression; 7. Patients switching to different scanning protocols during follow-up period resulting in discontinuous imaging assessment.

Design outcomes

Primary

MeasureTime frame
Accuracy;

Secondary

MeasureTime frame
Clinical Applicability;Readability;

Countries

China

Contacts

Public ContactLi Lijia

Yuebei People’s Hospital

1357610352@qq.com+86 751 6913416

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 20, 2026