brain glioma or metastatic tumor
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. No restriction on gender; 2. Pathologically confirmed or follow-up verified diagnosis of brain glioma or metastasis; 3. Pathologically confirmed or follow-up verified diagnosis of brain glioma or metastasis; 4. Complete clinical history, imaging data, and necessary follow-up information, including detailed treatment records, medication information, neurological function scores (such as KPS or ECOG scores), and corticosteroid usage; 5. Complete baseline MRI examination before treatment and at least one follow-up MRI examination after treatment; 6. Time interval between the two MRI examinations complies with the assessment time window recommended by RANO guidelines; 7. Complete MRI scanning sequences, including at least axial contrast-enhanced T1-weighted imaging, T2-weighted imaging, and FLAIR sequences.
Exclusion criteria
Exclusion criteria: 1. Incomplete clinical or imaging data, unable to determine accurate treatment regimen, treatment timing, or neurological function status; 2. Poor MRI image quality with significant motion artifacts, susceptibility artifacts, or other factors affecting tumor measurement; 3. MRI scanning does not comply with RANO standards, including missing necessary contrast-enhanced sequences, slice thickness >5mm, or scanning parameters severely deviating from standards; 4. Concurrent other intracranial lesions (such as cerebrovascular lesions, infections, etc.) that may interfere with treatment response assessment; 5. Presence of severe systemic diseases or complications that may affect imaging interpretation; 6. Post-treatment non-tumor-related intracranial changes (such as radiation necrosis, hemorrhage, infarction, etc.) that are difficult to differentiate from tumor progression; 7. Patients switching to different scanning protocols during follow-up period resulting in discontinuous imaging assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical Applicability;Readability; | — |
Countries
China
Contacts
Yuebei People’s Hospital