Hypoxic respiratory failure in newborns
Conditions
Interventions
Experimental group:Endotracheal instillation of 0.25 mg/kg budesonide (for 3 consecutive days) in combination with standard treatment
Control group:Conventional treatment
Sponsors
Qujing Maternity and Child Health Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. For diagnosing neonatal respiratory distress syndrome, it is necessary for the neonates who require invasive ventilator treatment and have not received PS treatment before admission. 2. For diagnosing neonatal meconium aspiration pneumonia, respiratory distress occurs within 6 hours after birth. 3. For diagnosing neonatal acute respiratory distress syndrome and those requiring invasive ventilator treatment. 4. For neonates with low-oxygen respiratory failure caused by other diseases and requiring invasive ventilator support treatment. 5. Parents/guardians give informed consent, agreeing to anonymize the data for research purposes.
Exclusion criteria
Exclusion criteria: 1. Severe congenital heart disease, severe congenital malformations or genetic metabolic disorders; 2. Parents do not wish to participate in the study; 3. Newborns die within 24 hours or are given up for treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Arterial Blood Gas (ABG) values;Duration of invasive ventilator use;Oxygen usage time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of hospital stay;Blood;Blood sugar; | — |
Countries
China
Contacts
Public ContactChuanfeng Li;Dan Li
Qujing Maternity and Child Health Hospital
Outcome results
None listed