Postoperative gastric cancer patients undergoing chemotherapy
Conditions
Interventions
Intervention group:Personalized nutritional management based on the Theoretical Domains Framework (TDF)
Sponsors
Jiangsu Province Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients who underwent gastroscopy and pathological biopsy before surgery and were pathologically diagnosed with gastric cancer. 2. The surgical procedure was radical gastrectomy. 3. The postoperative pathological diagnosis confirmed gastric cancer with TNM stage II–IV. 4. Received postoperative adjuvant chemotherapy. 5. Age and physical performance: 18–80 years old, Karnofsky Performance Status (KPS) score >=70, and an expected survival time of at least 6 months. 6. Nutritional intervention history: The patient had not previously received any systematic nutritional management intervention. 7. Home conditions: Having a stable residence and family support system, and being capable of completing home-based nutritional management. 8. Communication conditions: Able to use smartphones, WeChat, and other communication tools for remote follow-up. 9. Informed consent: Understands the purpose and procedures of the study, voluntarily participates, and signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Severe postoperative complications (such as anastomotic leakage and bleeding). 2. Severe comorbidities (such as serious cardiovascular, respiratory, renal, hepatic, or cerebrovascular diseases). 3. Presence of a second malignant tumor (unless curatively treated for more than 5 years). 4. Cognitive impairment or psychiatric disorder. 5. Diagnosis of visual, hearing, or speech impairment. 6. Participation in other nutrition-related studies within the past 30 days. 7. Special physiological condition: female patients who are pregnant or breastfeeding. 8. Compliance barrier: The investigator determined that the patient was unable to complete the study follow-up and intervention measures as required.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in patients’ nutritional status after a 3-month intervention; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events;Chemotherapy tolerance–related indicators;Changes in patients’ nutritional status after a 6-month intervention;Functional status assessment;Health-related quality of life; | — |
Countries
China
Contacts
Public ContactZhang Jie
Jiangsu Province Hospital of Chinese Medicine
Outcome results
None listed