Postpartum Hemorrhage
Conditions
Interventions
Treatment group:20 minutes of low-intensity focused ultrasound (LIFU) treatment will be Performed immediately after the third stage of labor and 12 hours postpartum, respectively.
Sham treatment group:20 minutes of low-intensity focused ultrasound (LIFU) treatment will be performed immediately after the third stage of labor and 12 hours postpartum, respectively, with no energy
Blank control group:Conventional oxytocin treatment
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Parturients aged 18–45 years who delivered vaginally and had a gestational age of 28–42 weeks; 2. Those without severe pregnancy-related comorbidities and complications; 3.Those without severe internal or surgical comorbidities; 4. Those who voluntarily agree to receive and cooperate with the completion of LIFU treatment and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with skin lesions in the lower abdominal region, extensive scars from previous surgeries, or poor acoustic access caused by pelvic chemotherapy, etc.; 2. Patients with poor wound healing in the treatment area, or skin ulcers/infections; 3. Patients with severe systemic diseases; 4. Patients with uterine malformations, uterine fibroids, excessive abdominal subcutaneous fat, severe peritoneal effusion, intestinal flatulence, or those in whom the uterine fundus cannot be satisfactorily palpated due to other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The amount of bleeding 2 hours and 24 hours after delivery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of postpartum hemorrhage;Fundal height, three-dimensional uterine volume on ultrasound;Hematological parameters (complete blood count, liver and renal function);Duration of postpartum lochia;Outcome of subsequent pregnancy;Ovarian function;Cutaneous reactions;Incidence of adverse events;Use of hemostatic interventions;Incidence of postpartum complications;Uterine smooth muscle contractile tension (animal study);Key targets and signaling pathways (transcriptomics, proteomics, metabolomics); | — |
Countries
China
Contacts
Public ContactLuo Xin
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed