Brain metastasis of lung cancer
Conditions
Interventions
desert type:None
lymphoid-enriched type:None
myeloid-enriched type:None
stromal-enriched type:None
balanced type:None
Sponsors
The First Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age not limited, gender not limited; 2. Have corresponding tumor samples and lymph node tissues in the pathology department, and the patient (or the guardian) has agreed to provide the archived tissue samples. 3. Diagnosed with brain metastasis of lung cancer, during the disease course, has received at least one cycle of systemic treatment based on immune checkpoint inhibitors.
Exclusion criteria
Exclusion criteria: 1. The clinical data is incomplete. Key diagnostic, treatment or follow-up information is lacking (such as the unclear pathological type of the primary lesion, absence of imaging data, loss of follow-up and no survival records), which cannot support statistical analysis. 2. Severe immunodeficiency or long-term use of immunosuppressants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall survival;Cluster of Differentiation 3(CD3);Ionized calcium-binding adapter molecule 1(IBA1);Platelet endothelial cell adhesion molecule-1 (CD31);Cluster of Differentiation 20(CD20);Cluster of Differentiation 56(CD56); | — |
Secondary
| Measure | Time frame |
|---|---|
| progression free survival;Medical Imaging; | — |
Countries
China
Contacts
Public ContactShi Yu
The First Affiliated Hospital of Army Medical University
Outcome results
None listed