Prostate Malignant Tumor
Conditions
Interventions
Gold Standard:Prostate biopsy pathology served as the gold standard for diagnosing prostate cancer in this study.
Index test:Prostate cancer risk prediction system based on an artificial intelligence multimodal data fusion model.
This system integrates MRI radiomic features, serum metabolomic features, and clin
Sponsors
Lishui Central Hospital
Eligibility
Sex/Gender
Male
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age = 50 years old; 2. PSA 4–10 ng/mL; 3. mpMRI or ultrasound suggests suspicious lesions; 4. No previous prostate biopsy and no history of confirmed prostate cancer; 5. No acute urinary tract infection or catheterization in the past 2 weeks; 6. Agree to provide blood samples and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with a history of other malignant tumors who received systemic treatment during the follow-up period; 2. Patients with severe cardiovascular, liver or kidney failure, or mental disorders who cannot cooperate; 3. Patients who have been taking 5a-reductase inhibitors for a long term (>3 months); 4. Patients with incomplete clinical data or key images/samples unavailable; 5. Patients whose MRI image quality is poor and cannot undergo radiomics analysis; 6. Patients who withdraw informed consent or are deemed unsuitable to continue by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic accuracy of the prostate cancer risk prediction model (AUC); | — |
Countries
China
Contacts
Public ContactChen Wang
Lishui Central Hospital
Outcome results
None listed