Severe Pneumonia
Conditions
Interventions
Severe Pneumonia Observation Group:None
Sponsors
Zhejiang Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Use enteral nutrition as the main feeding method (the energy provided by enteral nutrition is greater than that from parenteral nutrition); 2. Insert a gastric tube, nasojejunal tube, or perform a gastrostomy, and the enteral nutrition is administered smoothly; 3. The patient or the family member is informed and signs the consent form; 4. Meet the diagnostic criteria for severe pneumonia, and the diagnostic criteria typically rely on a series of clinical indicators. According to the "American IDSA/ATS Guidelines", they are divided into primary criteria and secondary criteria. Meeting one primary criterion or >= 3 secondary criteria is sufficient; 5. There is a risk of malnutrition in the nutritional screening (NRS 2002 >= 3 points), and there are indications for nutritional support treatment.
Exclusion criteria
Exclusion criteria: 1.Patients with a history of allergy to any component of enteral nutrition formulas; 2.Patients with severe cardiac, hepatic, or renal dysfunction, or with significant disturbances in internal homeostasis; 3.Patients with severe diabetes or those receiving high-dose corticosteroid therapy; 4.Pregnant or lactating women; 5.Patients with disorders of amino acid metabolism; 6.Patients with uncontrolled shock, hemodynamic instability, or inadequate tissue perfusion; 7.Patients with uncontrolled life-threatening hypoxemia, hypercapnia, or acidosis; 8.Patients with active upper gastrointestinal bleeding, significant gastrointestinal ischemia, high-output small intestinal fistula, or abdominal compartment syndrome; 9.Patients with gastrointestinal decompression drainage exceeding 500 mL per 6 hours; 10.Patients deemed unsuitable for participation by the clinical care team.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in diaphragm function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in muscle strength of the limbs;Intestinal barrier function indicators;Nutritional indicators;Inflammatory indicators;Immune indicators;Severity score of the disease; | — |
Countries
China
Contacts
Public ContactLei Shu
Zhejiang Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed