Thoracolumbar osteoporotic vertebral compression fractures, bone cement leakage in percutaneous vertebroplasty
Conditions
Interventions
Group with bone cement leakage observation:None
Sponsors
The Affiliated Hospital of Guangdong Medical University
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 50 years old, diagnosed with single-segment thoracolumbar (T10-L5) osteoporotic vertebral compression fractures (OVCF); 2. Planned or already undergone PVP surgery, with complete thin-layer CT (slice thickness <= 1mm, in DICOM format) and bone density test data before the operation; 3. Complete clinical data (including age, gender, duration of diabetes, history of using osteoporosis drugs, surgical records (puncture path, bone cement viscosity / injection volume)); 4. 24 hours after the operation, there are CT re-examination data (to assess leakage); 5. The patient or their family has given informed consent (for retrospective cohorts, informed consent can be waived as the data has been anonymized).
Exclusion criteria
Exclusion criteria: 1.Multiple segmental vertebral fractures, metastatic bone tumors, or vertebral body infections. 2.Poor quality of preoperative CT images (signal-to-noise ratio = 2 key clinical indicators that meet the exclusion criteria (such as bone mineral density T-score, cement volume injected). 4.Combined with severe cardiac, hepatic, or renal diseases, or coagulation dysfunction, and unable to comply with follow-up. 5.History of previous thoracolumbar spine surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone cement leakage; | — |
Countries
China
Contacts
Public ContactLiang Zhen
The Affiliated Hospital of Guangdong Medical University
Outcome results
None listed