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The effect of subclinical dose of esketamine on the incidence of postoperative chronic pain, a randomized, single blind controlled trial in thoracoscopic surgery

The effect of subclinical dose of esketamine on the incidence of postoperative chronic pain, a randomized, single blind controlled trial in thoracoscopic surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600120069
Enrollment
Unknown
Registered
2026-03-09
Start date
2024-09-18
Completion date
Unknown
Last updated
2026-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative chronic pain

Interventions

Experimental group:Intravenous injection of 0.4mg/kg esketamine in surgery
Control group:Do not use esketamine during surgery

Sponsors

Tianjin Medical University General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Men and women over the age of 18 2.ASA classification is grade I, II, or III 3.Patients who will undergo thoracoscopic surgery under general anesthesia 4.Patients understand this study clearly,voluntarily participate in, and sign an informed consent form by themselves

Exclusion criteria

Exclusion criteria: 1.Patients have a history of chronic pain or acute pain before surgery 2.Patients have been taking painkillers for a long time 3.Patients have severe liver and kidney dysfunction 4.Patients are in a state of depression and anxiety 5.Patients are pregnant or lactating women 6.Patients are allergic to the drugs involved in the study 7.Patients have participated in other drug clinical trials as a subject within the past 3 months 8.Researcher consider that patients should not participate in this trial

Design outcomes

Primary

MeasureTime frame
The incidence of postoperative chronic pain;Anxiety and Depression score;

Secondary

MeasureTime frame
Postoperative acute pain score;The quality of sleep;

Countries

China

Contacts

Public ContactYu Yonghao

Tianjin Medical University General Hospital

xieyegongstudy@sina.com+86 22 6036 1516

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 20, 2026