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Analysis and intervention of cortical-muscle coupling and muscle synergy in elderly sarcopenia

Analysis and intervention of cortical-muscle coupling and muscle synergy in elderly sarcopenia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600120037
Enrollment
Unknown
Registered
2026-03-09
Start date
2026-03-15
Completion date
Unknown
Last updated
2026-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sarcopenia

Interventions

Sarcopenia group:VR resistance training
Healthy elderly group:VR resistance training

Sponsors

Changzhou Dean Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: Sarcopenia elderly group: (1) Meet the diagnostic criteria of AWGS 2019: low muscle mass (male =12 seconds). (2) According to the Edinburgh Dominant Hand Scale, all the subjects were mainly right-handed, with normal vision after correction and no severe hearing impairment. (3) Possess a certain degree of mobility and be able to maintain a sitting position for at least 30 minutes. (4) Normal cognitive function. (5) No serious heart or lung diseases, neurological disorders or recent history of fractures. (6) The subjects sign the informed consent form. Healthy elderly group: (1) Age: 60 years old and above, with no gender restrictions. (2) According to the Edinburgh Handedness Inventory, all subjects are right-handed, have normal corrected vision, and no severe hearing impairment. (3) Have a certain degree of mobility and can maintain a sitting position for at least 30 minutes. (4) Normal cognitive function. (5) Subjects have signed the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Skull metal implants, missing skulls or damaged skin on the head, overly dense hair, etc. affect signal acquisition. (2) Poor compliance, stopping halfway or not cooperating. (3) History of mental illness. (4) Fracture or dislocation of the right upper limb or severe soft tissue injury within the past six months. (5) Secondary sarcopenia.

Design outcomes

Primary

MeasureTime frame
Cortical-muscular coupling(CMC);

Secondary

MeasureTime frame
Root mean square value(RMS);Fuzzy Approximate Entropy(fApEn);Oxygenated hemoglobin(HbO);Montreal Cognitive Assessment(MoCA);

Countries

China

Contacts

Public ContactHu Wenxuan

Changzhou Dean Hospital

15851969503@163.com+86 158 5196 9503

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 20, 2026