Postoperative delirium
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age >= 65 years old, gender not limited; 2.The hip fracture is planned to be treated under spinal anesthesia; 3.American Society of Anesthesiologists (ASA) classification: grades I to III; 4.Agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Old or peri-prosthetic fractures; 2.History of photosensitivity, or damaged or infected scalp in the frontal and parietal regions; 3.Epilepsy, stroke within 6 months; 4.Preoperative diagnosis of dementia, severe cognitive impairment or other mental disorders; 5.Alcohol or drug addicts; 6.Preoperative delirium; 7.Aphasia or hearing impairment preventing the ability to complete neuropsychological tests and EEG behavioral experiments; 8.Patients who had their surgeries prematurely terminated, were discharged, or were lost to follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cognitive function evaluation;Sleep Quality;Albumin Quotient;Resting-State Functional Connectivity of EEG;Task-State ERP Amplitude;Aß Oligomers;Brain-Derived Neurotrophic Factor; | — |
Countries
China
Contacts
Beijing Jishuitan Hospital, Capital Medical University