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Itraconazole for treating reactive skin capillary hyperplasia induced by camrelizumab: A single-arm study

Itraconazole for treating reactive skin capillary hyperplasia induced by camrelizumab: A single-arm study - Itraconazole for the treatment of camrelizumab induced RCCEP

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600120006
Enrollment
Unknown
Registered
2026-03-07
Start date
2026-03-07
Completion date
Unknown
Last updated
2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Reactive cutane-ous capillary endothelial proliferation

Interventions

Treatment Group:Take itraconazole capsules orally

Sponsors

Affiliated Hospital of Guangdong Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Patients who developed reactive cutaneous capillary hyperplasia after treatment with camrelizumab for tumors; 2. Fully understand this trial and voluntarily sign the informed consent form; 3. The age of the male or female subjects was 18 years old; 4. The liver function of the subject was normal.

Exclusion criteria

Exclusion criteria: 1. The patient is a pregnant or lactating woman; 2. Currently participating in any research involving intervention measures outside of regular clinical practice; 3. Currently taking drugs that have drug interactions with itraconazole, such as midazolam, triazolam, simvastatin, digoxin, warfarin, cyclosporine, tacrolimus, as well as erythromycin and clarithromycin, etc; 4. The researchers judged other situations that were not suitable for inclusion in the study.

Design outcomes

Primary

MeasureTime frame
The number of hemangiomas;The size of the hemangioma;The color of hemangioma;

Secondary

MeasureTime frame
Incidence of adverse drug reactions;

Countries

China

Contacts

Public ContactWu Wei

Affiliated Hospital of Guangdong Medical College

Wuwei1350187@126.com+86 150 1857 7451

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 14, 2026